陈蕾，女，博士，教授，博士生导师，主要从事病原检测与免疫分子机制研究。

相关研究成果共发表SCI文章30余篇，制订山东省地方标准6项，授权发明专利4件。主持国家及省部级项目10余项。获得山东省科学技术进步二等奖1项。

一、近几年主持的科研项目

1. 国家重点研发计划 猪三种重要疫病防控关键技术研发与应用2024-2027

2. 国家重点研发计划子课题 复杂生物体系代谢组的高通量超灵敏定性定量分析技术研究 2022-2027

3. 高端外国专家引进计划 微流控芯片技术在病原检测中的应用 2022-2024

4. 国家自然科学基金 FMDV 3C蛋白抑制II型IFN信号通路的机制研究，2017-2019

二、获得的科研奖励

2023年山东省科学技术进步奖二等奖：畜禽疫病核酸精准检测技术研发与应用 （1/10）

三、近几年发表的论文

(1) Kaini Zhang, Qingmei Li, Kun Wang, Qiaoli Zhang, Chengkun Ma, Guiwen Yang, Yanxia Xie, Michael G. Mauk, Shanji Fu,* and Lei Chen*.RPA-CRISPR-Cas-Mediated Dual Lateral Flow Assay for the Point-of-Care Testing of HPV16 and HPV18. Bioconjugate Chemistry. 2024 Nov 20;35(11):1797-1804.

(2) Qiaoli Zhang¹, Guanliu Yu ¹, Xinli Ding, Kaini Zhang, Wenbo Sun, Qingmei Li, Yunpeng Yi, Jianhua Wang, Xuehui Pang, Lei Chen*. A rapid simultaneous detection of duck hepatitis A virus 3 and novel duck reovirus based on RPA CRISPR Cas12a/Cas13a. Int J Biol Macromol. 2024 Aug;274(Pt 1):133246.

(3) Yujie Liu, Guanliu Yu, Hongkun Liang, Wenbo Sun, Lulu Zhang, Michael G Mauk, Hua Li, Lei Chen*. Detection and identification of SARS-CoV-2 and influenza a based on microfluidic technology. Anal Methods. 2024 Jul 11;16(27):4582-4589.

(4) Lei Chen ^a， Zhicheng Song ^a , Xintian Zhou  , Guiwen Yang ^a , Guanliu Yu ^a,*.Pathogenic bacteria and fungi in bioaerosols from specialized hospitals in Shandong province, East China. Environmental Pollution. 2023 Nov. 341:122922. doi:10.1016/j.envpol.2023.122922.

(5) Linyi Bai, Guanliu Yu, Yujie Liu, Muhammad Aizaz, Guiwen Yang, Lei Chen*. Common carp intelectin 3 (cITLN3) plays a role in the innate immune response. Fish & shellfish immunology. 2023 Oct:141:109057.

(6) Hua Wang, Yang Sun, Yuan Zhou, Yujie Liu, Shuo Chen, Wenbo Sun, Zidong Zhang, Junqing Guo, Cheng Yang, Zhengping Li, Lei Chen*. Unamplified system for sensitive and typing detection of ASFV by the cascade platform that CRISPR-Cas12a combined with graphene field-effect transistor. Biosens Bioelectron. 2023 Aug 25;240:115637.

(7) Yujie Liu, Hui Liu, Guanliu Yu, Wenbo Sun, Muhammad Aizaz, Guiwen Yang, Lei Chen*, One-tube RPA-CRISPR Cas12a/Cas13a rapid detection of methicillin-resistant Staphylococcus aureus, Analytica Chimica Acta.

(8) Xiangju Wu¹, Lei Chen ¹, Chao Sui, Yue Hu, Dandan Jiang, Fan Yang, Laura C. Miller, Juntong Li, Xiaoyan Cong, Nataliia Hrabchenko , Changhee Lee e, Yijun Du, Jing Qi*, 3Cpro of FMDV inhibits type II interferon-stimulated JAK-STAT signaling pathway by blocking STAT1 nuclear translocation, Virologica Sinica 38 (2023) 387–397.

(9) Linyi Bai, Hao Zhang, Yuan Zhou, Hongkun Liang, Shujun Chen, Xuehui Pang, G Mauk Michael, Lulu Zhang, Lei Chen*. Development of a surface plasmon resonance (SPR) assay for rapid detection of Aeromonas hydrophila. Analytical Biochemistry. 2023 Jun 1;670:115151.

(10) Linyi Bai, Yuan Zhou, Chen Sheng, Yizhi Yin, Yanru Chen, Xinli Ding, Guanliu Yu, Guiwen Yang, Lei Chen^*. Common carp Peptidoglycan Recognition Protein 2 (CcPGRP2) plays a role in innate immunity for defense against bacterial infections, Fish & shellfish immunology. 2023 Jan 20;133:108564.

(11) Y. Sun, C. Yang, X. Jiang, P. Zhang, S. Chen, F. Su, H. Wang, W. Liu, X. He, L. Chen, B. Man, Z. Li, High-intensity vector signals for detecting SARS-CoV-2 RNA using CRISPR/Cas13a couple with stabilized graphene field-effect transistor, Biosens Bioelectron, 222 (2023) 114979.